The diagnosis of a malignant bone tumour is based on tumour behaviour, cell type and microscopic features of malignancy. A bone tumor may be cancerous malignant or noncancerous benign. Discussion benign tumor staging uses arabic numbers 1,2,3. Osteochondroma 45% osteoid osteoma 10% enchondroma 10% haemangioma 10% nonossifying fibroma 4% osteoblastoma 2% chondroblastoma. Bone tumors clues and cues bone tumors clues and cues. Any skip lesions, regional lymph nodes, or distant metastases. It most commonly affects people within the first four decades of life with a larger probability of it occurring in the second and third decades. Columbia university, new york classification secondary metastases 95% primary 5%. Study 43 terms benign bone tumors flashcards quizlet. Pdf systematic approach to musculoskeletal benign tumors. The majority of the lesions can be diagnosed by the.
These include the thighbone femur, shinbone tibia, upper arm bone. Much of the data regarding the inci dence of benign bone tumors is based on material from series of biopsied or treated lesions. Most benign giant cell tumors of bone are treated by radical curettage and packing with methyl methacrylate or by bone graft. Contrary to what most people expect, benign bone tumors occur most often in people less than 30 years old. Tumors are abnormal masses of tissue created by uncontrolled cell division.
Pdf global incidence of primary malignant bone tumors. Benign bone tumor prevalence of benign bone tumors. Secondary tumors can be further subdivided into metastatic tumors tumors resulting from contiguous spread of adjacent soft tissue neoplasms tumors representing malignant transformation of the preexisting benign lesions. A growing bone tumor even a benign tumor destroys healthy tissue and weakens bone, making it more vulnerable to fracture.
A growing tumor may replace healthy tissue with abnormal tissue. The most common malignant bone tumours found in the foot did not start there. Benign bone tumours and tumourlike lesions are much more common than primary malignant bone tumours. A periosteal reaction is a nonspecific reaction and will occur whenever the periosteum is irritated by a malignant tumor, benign tumor, infection or trauma. Primary malignant bone tumours service adults and adolescents commissioner lead. They are much more likely to have spread from another location in the body, something known as metastasis. Primary bone neoplasms are extremely rare, accounting for only 0.
Learn more about the symptoms, risk factors, diagnosis, types, treatment, and outlook for bone cancer. The standard care of treatment of gct in our institution is the extended. Management of benign bone tumours orthopaedics and trauma. Although any bone can be involved, osteoblastoma arises predominantly in the axial skeleton with spinal lesions constituting onethird of reported cases. Pathological fractures from benign tumours icm robertson feb. Most primary bone tumors are seen in patients in patients 30 years we must always include metastases and myeloma in the differential diagnosis.
Approach to bone tumor diagnosis general considerations. Based on the lodwick classification an overview of the three main types of bone. It does not invade nearby tissue or spread to other parts of the body the. A tumor is an abnormal growth of cells that serves no purpose. Most bone tumors are benign, and unlikely to spread. The pericentromeric inversion, inv 6p25q, is a novel. Guidelines for histopathological specimen examination and. Nevertheless some of the benign tumours are capable of distant metastasis e. A tumor is a lump or mass of tissue that forms when cells divide uncontrollably.
The who classification of bone tumors springerlink. They may be benign noncancerous or malignant cancerous. Important factors in diagnosis of a bone tumor include patient age and gender. Malignant tumors can secrete substances that cause effects throughout the body, such as fatigue and weight loss. Benign tumors are selfcontained, nonlethal, and grow more slowly than malignant ones. Bone tumors pdf bone tumors represent a unique group of pathologic conditions for which little. Also characteristic of osteosarcoma is the frequency with which the tumor breaks out of the medullary canal to invade the soft tissues and form a. They can occur in any bone, but they usually are found in the biggest ones. Osteoblastoma is a rare, benign bone tumour accounting for 14% of bone tumours. The blood filled cysts are divided by connective tissue. There are several types of benign tumours that can be classified by the type of matrix that the tumour cells produce. When a bone tumor is cancerous, it is either a primary bone cancer or a secondary bone cancer.
Both the management of individual patients and the comparison between groups of bone tumor cases can be seriously complicated by uncertainty with regard to the definition of the terms used in. Bone tumors are caused by an abnormal growth of cells. Benign and malignant bone tumors uconn musculoskeletal. Primary malignant bone tumours account for 1% of cancer deaths. Although rare, bone tumors can occur in the foot and ankle. By alina maria sisu, loredana gabriela stana, codruta ileana petrescu, romulus. Bone tumors can be divided into primary and secondary. The musculoskeletal tumor society staging system for benign bone tumors has three.
Initial evaluation carried out in 4 phases 1 st phase involves high index of suspicion for tumors routine xrays routine lab facilities meticulous. To reduce recurrence rate, surgeons often prefer using an adjuvant. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Appropriate discrimination of benign versus malignant bone. Benign bone tumors are staged according to their radiographic appearance and apparent clinical behavior. A stepbystep diagnostic algorithm of bone tumors and. A primary bone cancer actually begins in bone while a secondary bone cancer begins somewhere else in the body and then. Because most of the tumor is the cartilage cap, the xray opacity is smaller. Benign tumors are usually not lifethreatening and, in most cases, will not spread to other parts of the body. A benign tumor is not a malignant tumor, which is cancer. Any information contained in this pdf file is automatically generated from digital material.
The incidence for the three most common excluding myeloma is only nine per million of population per year. Benign bone tumours free download as powerpoint presentation. Fortunately, the majority of tumors that originate in the bones are benign, meaning that the tumor is very unlikely to spread from its original site to a new location. Aneurysmal bone cysts abcs are fairly rare benign cystic lesions, accounting for approximately 9. About us introductory course case studies unknoun slides. Gct is a benign primary bone tumor which is known to cause local recurrence as well as distant metastases. The global incidence of primary malignant bone tumors shows a speci. Bone tumors may be classified as primary tumors, which originate in bone or from bonederived cells and tissues, and secondary tumors which originate in other sites and spread metastasize to the. Benign bone tumours are rare, occurring most commonly in skeletally immature. According to the american academy of orthopaedic surgeons aaos, the most common type of benign bone tumor is an. A bone tumor is an abnormal growth of cells within a bone.796 1334 193 708 1107 907 1489 37 758 667 842 654 275 533 1245 2 1030 400 851 869 664 220 281 636 632 945 309 942 1235 433 212 1217 553